All you need to know about end-stage liver disease

There are typically four stages of liver damage, from inflammation to end-stage liver disease (ESLD), where any ailment that results in inflammation or liver damage is referred to as a liver disease. Damage to the liver can accumulate as liver disease advances through its several stages, and each stage individually affects your liver’s ability to carry out its activities properly.

The following are the four stages of liver disease or damage:

  • Inflammation
  • Fibrosis
  • Cirrhosis
  • End-stage liver disease (ESLD)

 

Significant liver damage has been caused by hepatitis C, which is in its last stages. The hepatitis C virus often begins by causing inflammation before eventually scarring the liver over a period of years (cirrhosis). Before developing cirrhosis, people can experience mild or no symptoms of liver disease for years or even decades.
Decompensated cirrhosis, also known as stage 4 advanced cirrhosis, and chronic liver failure brought on by hepatitis C are two conditions that fall under the umbrella term of ESLD. At this point, the liver’s capacity to function has drastically decreased. Ascites, a type of abdominal swelling, and hepatic encephalopathy are side effects of ESLD (reduced brain function). The only treatment for ESLD that can be reversed is a liver transplant.

During a transplant, a surgeon swaps out the diseased liver with a healthy donor’s liver. The goal of cirrhosis treatment is to stop the condition from getting worse. It could be able to lessen or stop the damage.

Symptoms of ESLD

Simple bruising or bleeding, persistent or recurrent yellowing of the skin or eyes are all signs of end-stage liver disease.

Strong itchiness, pain in the belly or legs, nausea, decreased appetite, edema from an accumulation of fluid, memory and attention problems are the other symptoms of ESLD.

When the liver loses all or most of its function, liver failure arises from the typical course of cirrhosis. Those who have cirrhosis may also go through the following:

• Bleeding in the digestive system brought on by an accumulation of toxins in the blood;

• Esophageal varices, a condition characterized by dilated veins in the tube linking the throat and stomach (hepatic encephalopathy).

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