Here’s all about end-stage renal disease

CHANDIGARH
When chronic kidney disease the gradual loss of kidney function reaches an advanced stage, end-stage renal disease, also known as end-stage kidney disease or kidney failure, develops. Your kidneys no longer perform well as well as they don’t support your body’s needs if you have end-stage renal disease.

Wastes and surplus fluids are filtered from your blood and expelled as urine by your kidneys. When your kidneys lose their filtering ability, your body might accumulate harmful levels of fluid, electrolytes, and toxins.
Dialysis or a kidney transplant are required to keep alive if you have end-stage renal disease. However, you can choose to treat your symptoms with conservative care, aiming for the best quality of life possible in the time you have left.
Symptoms 
You may have no indications or symptoms early on in chronic renal disease. The following signs and symptoms may appear as chronic kidney disease advances to end-stage renal disease:
  • Nausea
  • Vomiting
  • Appetite loss.
  • Weakness and exhaustion
  • Changes in the amount of urine you produce
  • If fluid builds up around the heart’s lining, it might cause chest pain.
  • If fluid builds up in the lungs, it can cause shortness of breath.
  • Foot and ankle swelling
  • Hypertension (high blood pressure) that is difficult to control
  • Headaches
  • Sleeping problems
  • Mental acuity has deteriorated.
  • Muscle cramps and twitches
  • Itching that doesn’t go away
  • Tastes metallic
Kidney disease can be caused by a variety of diseases and disorders, including: 
  • Diabetes type 1 or type 2
  • Blood pressure that is too high
  • Glomerulonephritis  is a condition in which the filtration units of the kidney become inflamed
  • An inflammation of the tubules and surrounding tissues of the kidney is known as interstitial nephritis
  • Other inherited kidney illnesses, such as polycystic kidney disease
  • Long-term obstruction of the urinary tract caused by disorders such as an enlarged prostate, kidney stones, and several malignancies.
  • Vesicoureteral reflux is a condition in which urine backs up into the kidneys.
  • Pyelonephritis is a type of recurrent kidney infection
Risk factors include: 
  • Blood pressure that is too high
  • Tobacco consumption
  • Kidney failure in the family
  • Getting older
  • Use of potentially kidney-damaging drugs on a regular basis
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